[Complete Response Obtained with First-Line Therapy as S-1, Followed by Second-Line 5'-DFUR Plus Paclitaxel Therapy in a Patient with Multiple Liver and Lymphnode Metastases from Gastric Cancer.] Gan to kagaku ryoho. Cancer & chemotherapy [Gan To Kagaku Ryoho] Journal article | | Title | [Complete Response Obtained with First-Line Therapy as S-1, Followed by Second-Line 5'-DFUR Plus Paclitaxel Therapy in a Patient with Multiple Liver and Lymphnode Metastases from Gastric Cancer.] | | Author(s) | Kitajima Y, Yakabe T, Ohtsuka T, Tanaka M, Sato S, Nakafusa Y, Miyazaki K | | Institution | Dept. of Surgery, Saga University Faculty of Medicine. | | Source | Gan To Kagaku Ryoho 2009 May; 36(5):851-4. | | Abstract | A 82-year-old man with advanced gastric cancer underwent distal gastrectomy in January 2006. The histological diagnosis was poorly-differentiated adenocarcinoma, T2(MP), pN2, sH0, sP0, CY0; fStage III A. Three months after the operation, two metastatic nodules were noticed on the liver. The patient was treated with S-1 in April 2006. After the 8 courses of S-1 treatment, a complete response was achieved. However, a lymphnode metastasis was newly found adjacent to the remnant stomach 2months after the complete response to S-1. 5'-DFUR+paclitaxel combination therapy was then performed. After the 2courses, the metastatic lymphnode completely disappeared. We continued a total of 18 courses of the 5'-DFUR+paclitaxel therapy approximately for 1 year without critical drug toxicity. The patient has been alive without any recurrent site. Thus 5'-DFUR+paclitaxel as a second-line therapy following S-1 should be recommended for a gastric cancer patient with a recurrent tumor. | | Language | jpn | | Pub Type(s) | English Abstract
Journal Article
| | PubMed ID | 19461193 |
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